5D28
Complex of GM-CSF/IL-2 inhibition factor with Granulocyte-macrophage colony-stimulating factor
Summary for 5D28
Entry DOI | 10.2210/pdb5d28/pdb |
Related | 5D22 |
Descriptor | GM-CSF/IL-2 inhibition factor, Granulocyte-macrophage colony-stimulating factor, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total) |
Functional Keywords | signaling protein, cytokine, host-pathogen interactions, immunology, viral protein |
Biological source | Orf virus (ORFV) More |
Total number of polymer chains | 4 |
Total formula weight | 87805.03 |
Authors | Felix, J.,Savvides, S.N. (deposition date: 2015-08-05, release date: 2016-11-16, Last modification date: 2024-10-16) |
Primary citation | Felix, J.,Kandiah, E.,De Munck, S.,Bloch, Y.,van Zundert, G.C.,Pauwels, K.,Dansercoer, A.,Novanska, K.,Read, R.J.,Bonvin, A.M.,Vergauwen, B.,Verstraete, K.,Gutsche, I.,Savvides, S.N. Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF. Nat Commun, 7:13228-13228, 2016 Cited by PubMed: 27819269DOI: 10.1038/ncomms13228 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.845 Å) |
Structure validation
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