5CN0
Artificial HIV fusion inhibitor AP2 fused to the C-terminus of gp41 NHR
Summary for 5CN0
Entry DOI | 10.2210/pdb5cn0/pdb |
Related | 5CMU 5CMZ |
Descriptor | Envelope glycoprotein,AP2, MAGNESIUM ION, DI(HYDROXYETHYL)ETHER, ... (4 entities in total) |
Functional Keywords | enfuvirtide, hiv fusion inhibitor, ap2, gp41, 6-hb, viral protein |
Biological source | Human immunodeficiency virus 1 (HIV1) More |
Total number of polymer chains | 1 |
Total formula weight | 8741.31 |
Authors | |
Primary citation | Zhu, X.,Zhu, Y.,Ye, S.,Wang, Q.,Xu, W.,Su, S.,Sun, Z.,Yu, F.,Liu, Q.,Wang, C.,Zhang, T.,Zhang, Z.,Zhang, X.,Xu, J.,Du, L.,Liu, K.,Lu, L.,Zhang, R.,Jiang, S. Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy. Sci Rep, 5:13028-13028, 2015 Cited by PubMed: 26286358DOI: 10.1038/srep13028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.901 Å) |
Structure validation
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