5CA7

Human DNA polymerase lambda- MgdGTP binary and complex with 6 paired DNA

Summary for 5CA7

• Entry DOI: 10.2210/pdb5ca7/pdb
• Related: 4W5D
• Descriptor: DNA polymerase lambda, DNA (5'-D(*CP*AP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*TP*AP*CP*TP*G)-3'), ... (7 entities in total)
• Functional Keywords: dna polymerase lambda, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 78942.11

Authors

Liu, M.S.,Tsai, M.D. (deposition date: 2015-06-29, release date: 2016-02-24, Last modification date: 2023-11-08)

• Primary citation: Liu, M.S.,Tsai, H.Y.,Liu, X.X.,Ho, M.C.,Wu, W.J.,Tsai, M.D.; Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda; J.Am.Chem.Soc., 138:2389-2398, 2016; PubMed: 26836966; DOI: 10.1021/jacs.5b13368

Experimental method

X-RAY DIFFRACTION (2.522 Å)