5C9V

Structure of human Parkin G319A

Summary for 5C9V

• Entry DOI: 10.2210/pdb5c9v/pdb
• Descriptor: E3 ubiquitin-protein ligase parkin, ZINC ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: parkin, ubiquitin, e3 ligase, rbr, parkinson's disease, mitophagy, cell signalling, signaling protein
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm, cytosol : O60260
• Total number of polymer chains: 1
• Total formula weight: 38268.06

Authors

Wauer, T.,Komander, D. (deposition date: 2015-06-29, release date: 2015-07-22, Last modification date: 2024-01-10)

• Primary citation: Wauer, T.,Simicek, M.,Schubert, A.,Komander, D.; Mechanism of phospho-ubiquitin-induced PARKIN activation.; Nature, 524:370-374, 2015; PubMed: 26161729; DOI: 10.1038/nature14879

Experimental method

X-RAY DIFFRACTION (2.35 Å)