4ZV8
Structure of CYP2B6 (Y226H/K262R) with additional mutation Y244W in complex with alpha-Pinene
Summary for 4ZV8
Entry DOI | 10.2210/pdb4zv8/pdb |
Related | 3IBD 3QOA 3QU8 3UA5 4I91 4RQL 4RRT |
Descriptor | Cytochrome P450 2B6, PROTOPORPHYRIN IX CONTAINING FE, (+)-alpha-Pinene, ... (5 entities in total) |
Functional Keywords | cytochrome p450 2b6, monoxygenase, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 56410.91 |
Authors | Liu, J.,Shah, M.B.,Stout, C.D.,Halpert, J.R. (deposition date: 2015-05-18, release date: 2016-03-30, Last modification date: 2023-09-27) |
Primary citation | Liu, J.,Shah, M.B.,Zhang, Q.,Stout, C.D.,Halpert, J.R.,Wilderman, P.R. Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations. Biochemistry, 55:1997-2007, 2016 Cited by PubMed: 26982502DOI: 10.1021/acs.biochem.5b01330 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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