4RQL
Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with a monoterpene - sabinene
Summary for 4RQL
Entry DOI | 10.2210/pdb4rql/pdb |
Related | 3IBD 3QOA 3QU8 3UA5 4I91 |
Descriptor | Cytochrome P450 2B6, PROTOPORPHYRIN IX CONTAINING FE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ... (6 entities in total) |
Functional Keywords | p450, cytochrome p450 2b6, monooxygenase, membrane protein, cyp2b6, endoplasmic reticulum, heme, iron, metal binding, microsome, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P20813 |
Total number of polymer chains | 2 |
Total formula weight | 113889.02 |
Authors | Shah, M.B. (deposition date: 2014-11-03, release date: 2015-01-28, Last modification date: 2024-02-28) |
Primary citation | Shah, M.B.,Wilderman, P.R.,Liu, J.,Jang, H.H.,Zhang, Q.,Stout, C.D.,Halpert, J.R. Structural and Biophysical Characterization of Human Cytochromes P450 2B6 and 2A6 Bound to Volatile Hydrocarbons: Analysis and Comparison. Mol.Pharmacol., 87:649-659, 2015 Cited by PubMed: 25585967DOI: 10.1124/mol.114.097014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.105 Å) |
Structure validation
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