4ZUP

Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a hydroxamate inhibitor

Summary for 4ZUP

Related4ZUM 4ZUN 4ZUO 4ZUQ 4ZUR
DescriptorAcetylpolyamine aminohydrolase, ZINC ION, POTASSIUM ION, ... (7 entities in total)
Functional Keywordsacetylpolyamine amidohydrolase, arginase fold, enzyme-inhibitor complex, polyamine, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceMycoplana ramosa
Total number of polymer chains2
Total molecular weight74038.73
Authors
Decroos, C.,Christianson, D.W. (deposition date: 2015-05-17, release date: 2015-07-29, Last modification date: 2019-12-25)
Primary citation
Decroos, C.,Christianson, D.W.
Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase.
Biochemistry, 54:4692-4703, 2015
PubMed: 26200446 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.5b00536
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.421 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1532 0.3% 2.2%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
169963
PDB entries from 2020-10-14