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4ZUN

Crystal structure of acetylpolyamine amidohydrolase from Mycoplana ramosa in complex with a thiol inhibitor

Summary for 4ZUN
Entry DOI10.2210/pdb4zun/pdb
Related4ZUM 4ZUO 4ZUP 4ZUQ 4ZUR
DescriptorAcetylpolyamine aminohydrolase, 5-[(3-aminopropyl)amino]pentane-1-thiol, POTASSIUM ION, ... (7 entities in total)
Functional Keywordsacetylpolyamine amidohydrolase, arginase fold, enzyme-inhibitor complex, polyamine, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceMycoplana ramosa
Total number of polymer chains2
Total formula weight73754.72
Authors
Decroos, C.,Christianson, D.W. (deposition date: 2015-05-17, release date: 2015-07-29, Last modification date: 2023-09-27)
Primary citationDecroos, C.,Christianson, D.W.
Design, Synthesis, and Evaluation of Polyamine Deacetylase Inhibitors, and High-Resolution Crystal Structures of Their Complexes with Acetylpolyamine Amidohydrolase.
Biochemistry, 54:4692-4703, 2015
Cited by
PubMed: 26200446
DOI: 10.1021/acs.biochem.5b00536
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.4 Å)
Structure validation

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