4ZTV

Non-anthranilate-like inhibitor (TAMU-A7) complexed with anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis in absence of PRPP

4ZTV の概要

• エントリーDOI: 10.2210/pdb4ztv/pdb
• 関連するPDBエントリー: 3QR9 3QSA
• 分子名称: Anthranilate phosphoribosyltransferase, 4,4,4-trifluoro-1-(4-methoxyphenyl)butane-1,3-dione (3 entities in total)
• 機能のキーワード: non-anthranilate-like inhibitor, trpd, anprt, transferase-transferase inhibitor complex, structural genomics, tb structural genomics consortium, tbsgc, transferase/transferase inhibitor
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 78190.13

構造登録者

Evans, G.L.,Eom, J.,Baker, E.N.,Lott, J.S.,TB Structural Genomics Consortium (TBSGC) (登録日: 2015-05-15, 公開日: 2016-05-25, 最終更新日: 2023-09-27)

• 主引用文献: Evans, G.L.,Bulloch, E.M.M.,Eom, J.,Castell, A.,Short, F.L.,Baker, E.N.,Lott, J.S.; Bioactive non-anthranilate-like fragment-like inhibitor provides alternative starting point for inhibitor design against anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis.; To be Published,

実験手法

X-RAY DIFFRACTION (2.01 Å)