4ZTV
Non-anthranilate-like inhibitor (TAMU-A7) complexed with anthranilate phosphoribosyltransferase (trpD) from Mycobacterium tuberculosis in absence of PRPP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000162 | biological_process | tryptophan biosynthetic process |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004048 | molecular_function | anthranilate phosphoribosyltransferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000162 | biological_process | tryptophan biosynthetic process |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004048 | molecular_function | anthranilate phosphoribosyltransferase activity |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0016763 | molecular_function | pentosyltransferase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue TA7 A 400 |
| Chain | Residue |
| A | MET86 |
| A | ARG193 |
| A | HOH648 |
| A | HIS136 |
| A | ASN138 |
| A | ALA179 |
| A | PRO180 |
| A | HIS183 |
| A | TYR186 |
| A | ARG187 |
| A | ALA190 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue TA7 B 400 |
| Chain | Residue |
| B | MET86 |
| B | HIS136 |
| B | ASN138 |
| B | PRO180 |
| B | HIS183 |
| B | TYR186 |
| B | ARG187 |
| B | ALA190 |
| B | ARG193 |
| B | GLY206 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00211 |
| Chain | Residue | Details |
| A | GLY107 | |
| A | ASP251 | |
| A | GLU252 | |
| B | GLY107 | |
| B | GLY110 | |
| B | THR115 | |
| B | ASN117 | |
| B | SER119 | |
| B | LYS135 | |
| B | ASN138 | |
| B | GLY147 | |
| A | GLY110 | |
| B | ARG193 | |
| B | ASP251 | |
| B | GLU252 | |
| A | THR115 | |
| A | ASN117 | |
| A | SER119 | |
| A | LYS135 | |
| A | ASN138 | |
| A | GLY147 | |
| A | ARG193 |
