4ZRU

X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP) in complex with 3-[2-[(2S)-pyrrolidin-2-yl]ethynyl]pyridine (TI-5180)

4ZRU の概要

• エントリーDOI: 10.2210/pdb4zru/pdb
• 分子名称: Acetylcholine-binding protein, PHOSPHATE ION, 3-[(2S)-pyrrolidin-2-ylethynyl]pyridine, ... (4 entities in total)
• 機能のキーワード: nicotinic, acetylcholine, ls-achbp, acetylcholine binding protein
• 由来する生物種: Lymnaea stagnalis (Great pond snail)
• 細胞内の位置: Secreted: P58154
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 251266.93

構造登録者

Bobango, J.,Sankaran, B.,Park, J.F.,Wu, J.,Talley, T.T. (登録日: 2015-05-12, 公開日: 2015-05-27, 最終更新日: 2023-09-27)

• 主引用文献: Talley, T.T.; Comparisons of Binding Affinities for Neuronal Nicotinic Receptors (NNRs) and AChBPs, and Structural Features of a High-Affinity, Non-selective NNR Ligand-AChBP Co-crystal Structure; To be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)