4ZHN
Crystal Structure of AlkB T208A mutant protein in complex with Co(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T
Summary for 4ZHN
Entry DOI | 10.2210/pdb4zhn/pdb |
Descriptor | methylated trinucleotide DNA T-meA-T, Alpha-ketoglutarate-dependent dioxygenase AlkB, COBALT (II) ION, ... (5 entities in total) |
Functional Keywords | beta jellyroll, oxidoreductase-dna complex, dna repair enzyme, structural genomics, psi-2, protein structure initiative, northeast structural genomics consortium, nesg, oxidoreductase/dna |
Biological source | Escherichia coli (strain K12) More |
Total number of polymer chains | 2 |
Total formula weight | 24677.65 |
Authors | Ergel, B.,Yu, B.,Vorobiev, S.M.,Forouhar, F.,Hunt, J.F.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2015-04-25, release date: 2015-12-23, Last modification date: 2023-09-27) |
Primary citation | Hall, M.L.,Ergel, B.,Miller, E.B.,Yu, B.,Rinaldo, D.,Hunt, J.F.,Friesner, R. DFT Studies of the Rate-Limiting Step in the Reaction Cycle of the Fe/2OG Dioxygenase AlkB and Related Experimental Studies To be published, |
Experimental method | X-RAY DIFFRACTION (1.333 Å) |
Structure validation
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