4Z6E

Structure of human DNA polymerase beta 279NA mutant complexed with G in the template base paired with incoming non-hydrolyzable TTP and MANGANESE

Summary for 4Z6E

• Entry DOI: 10.2210/pdb4z6e/pdb
• Related: 4Z6C 4Z6D 4Z6F
• Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*GP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... (8 entities in total)
• Functional Keywords: dna polymerase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 48300.90

Authors

Koag, M.-C.,Lee, S. (deposition date: 2015-04-04, release date: 2016-04-13, Last modification date: 2023-09-27)

• Primary citation: Koag, M.C.,Lee, S.; Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication by human DNA polymerase beta.; Biochem. J., 475:571-585, 2018; PubMed: 29301983; DOI: 10.1042/BCJ20170787

Experimental method

X-RAY DIFFRACTION (2.752 Å)