4Z32

Crystal Structure of the FERM-SH2 Domains of Jak2

Summary for 4Z32

• Entry DOI: 10.2210/pdb4z32/pdb
• Descriptor: Tyrosine-protein kinase JAK2 (2 entities in total)
• Functional Keywords: jak-stat, ferm domain, sh2 domain, cytokine receptor, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Endomembrane system ; Peripheral membrane protein : O60674
• Total number of polymer chains: 8
• Total formula weight: 461453.18

Authors

McNally, R.,Eck, M.J. (deposition date: 2015-03-30, release date: 2016-06-22, Last modification date: 2023-09-27)

• Primary citation: McNally, R.,Toms, A.V.,Eck, M.J.; Crystal Structure of the FERM-SH2 Module of Human Jak2.; Plos One, 11:e0156218-e0156218, 2016; PubMed: 27227461; DOI: 10.1371/journal.pone.0156218

Experimental method

X-RAY DIFFRACTION (3.04 Å)