4YXR
CRYSTAL STRUCTURE OF PKA IN COMPLEX WITH inhibitor.
Summary for 4YXR
Entry DOI | 10.2210/pdb4yxr/pdb |
Descriptor | cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 3-methyl-2H-indazole, ... (4 entities in total) |
Functional Keywords | complex (phosphotransferase-inhibitor) complex, transferase |
Biological source | Bos taurus (Bovine) More |
Cellular location | Cytoplasm : P00517 |
Total number of polymer chains | 2 |
Total formula weight | 43065.98 |
Authors | Schiffer, A.,Wendt, K.U. (deposition date: 2015-03-23, release date: 2015-05-27, Last modification date: 2015-06-03) |
Primary citation | Pilger, J.,Mazur, A.,Monecke, P.,Schreuder, H.,Elshorst, B.,Bartoschek, S.,Langer, T.,Schiffer, A.,Krimm, I.,Wegstroth, M.,Lee, D.,Hessler, G.,Wendt, K.U.,Becker, S.,Griesinger, C. A combination of spin diffusion methods for the determination of protein-ligand complex structural ensembles. Angew.Chem.Int.Ed.Engl., 54:6511-6515, 2015 Cited by PubMed: 25877959DOI: 10.1002/anie.201500671 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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