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4YTN

Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with N-[3-(pentafluorophenoxy)phenyl]-2-(trifluoromethyl)benzamide

Summary for 4YTN
Entry DOI10.2210/pdb4ytn/pdb
Related4YSX 4YSY 4YSZ 4YT0 4YTM 4YTP 4YXD
DescriptorSuccinate dehydrogenase flavoprotein, PROTOPORPHYRIN IX CONTAINING FE, N-[3-(pentafluorophenoxy)phenyl]-2-(trifluoromethyl)benzamide, ... (12 entities in total)
Functional Keywordsoxidoreductase, rhodoquinol-fumarate reductase, complex ii, inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceAscaris suum (Pig roundworm)
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Total number of polymer chains8
Total formula weight288047.72
Authors
Harada, S.,Shiba, T.,Sato, D.,Yamamoto, A.,Nagahama, M.,Yone, A.,Inaoka, D.K.,Sakamoto, K.,Inoue, M.,Honma, T.,Kita, K. (deposition date: 2015-03-18, release date: 2015-08-05, Last modification date: 2023-11-08)
Primary citationHarada, S.,Shiba, T.,Sato, D.,Yamamoto, A.,Nagahama, M.,Yone, A.,Inaoka, D.K.,Sakamoto, K.,Inoue, M.,Honma, T.,Kita, K.
New Insights into the Design of Inhibitors Targeted for Parasitic Anaerobic Energy Metabolism
To Be Published,
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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