4YOL
Human fibroblast growth factor-1 C16S/A66C/C117A/P134A
Summary for 4YOL
Entry DOI | 10.2210/pdb4yol/pdb |
Related | 1JQZ 1RG8 2AFG 3FJK 3HOM 4Q9G 4QAL |
Descriptor | Fibroblast growth factor 1, CITRATE ANION, IMIDAZOLE, ... (4 entities in total) |
Functional Keywords | fibroblast growth factor-1, cysteine-free mutant, fgf-1, intramolecular disulfide, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 33998.97 |
Authors | Xia, X.,Blaber, M. (deposition date: 2015-03-11, release date: 2016-03-16, Last modification date: 2019-02-13) |
Primary citation | Xia, X.,Kumru, O.S.,Blaber, S.I.,Middaugh, C.R.,Li, L.,Ornitz, D.M.,Sutherland, M.A.,Tenorio, C.A.,Blaber, M. Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application. J.Pharm.Sci., 105:1444-1453, 2016 Cited by PubMed: 27019961DOI: 10.1016/j.xphs.2016.02.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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