4YN0

Crystal structure of APP E2 domain in complex with DR6 CRD domain

4YN0 の概要

• エントリーDOI: 10.2210/pdb4yn0/pdb
• 分子名称: Tumor necrosis factor receptor superfamily member 21, Amyloid beta A4 protein, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: alzheimer, neuron pruning, amyloid precursor protein, apoptosis-cell adhesion complex, apoptosis/cell adhesion
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48427.18

構造登録者

Xu, K.,Nikolov, D. (登録日: 2015-03-08, 公開日: 2015-04-15, 最終更新日: 2020-07-29)

• 主引用文献: Xu, K.,Olsen, O.,Tzvetkova-Robev, D.,Tessier-Lavigne, M.,Nikolov, D.B.; The crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation.; Genes Dev., 29:785-790, 2015; PubMed: 25838500; DOI: 10.1101/gad.257675.114

実験手法

X-RAY DIFFRACTION (2.2 Å)