4YM4

Truncated Human TIFA in complex with its Thr9 phosphorylated N-terminal peptide 1-15

Summary for 4YM4

• Entry DOI: 10.2210/pdb4ym4/pdb
• Descriptor: TRAF-interacting protein with FHA domain-containing protein A (2 entities in total)
• Functional Keywords: complex, fha domian, adaptor, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 18303.88

Authors

Weng, J.H.,Wei, T.Y.W.,Hsieh, Y.C.,Huang, C.C.F.,Wu, P.Y.G.,Chen, E.S.W.,Huang, K.F.,Chen, C.J.,Tsai, M.D. (deposition date: 2015-03-06, release date: 2015-10-21, Last modification date: 2015-10-28)

• Primary citation: Weng, J.H.,Hsieh, Y.C.,Huang, C.C.,Wei, T.Y.,Lim, L.H.,Chen, Y.H.,Ho, M.R.,Wang, I.,Huang, K.F.,Chen, C.J.,Tsai, M.D.; Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses.; Biochemistry, 54:6219-6229, 2015; PubMed: 26389808; DOI: 10.1021/acs.biochem.5b00500

Experimental method

X-RAY DIFFRACTION (3.12 Å)