4YJV

THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000250

Summary for 4YJV

• Entry DOI: 10.2210/pdb4yjv/pdb
• Descriptor: Tyrosine-protein kinase SYK, 3-[6-({4-[ethyl(1H-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1H-indazol-1-yl]propan-1-ol (3 entities in total)
• Functional Keywords: syk, non-receptor tyrosine kinase, spleen tyrosine kinase, transferase, phosphorylation, transferase-transferase inhibitor complex
• Biological source: Homo sapiens (Human)
• Cellular location: Cell membrane : P43405
• Total number of polymer chains: 1
• Total formula weight: 33259.10

Authors

Somers, D.O.,Neu, M.,Stuckey, J. (deposition date: 2015-03-03, release date: 2015-10-14, Last modification date: 2024-11-20)

• Primary citation: Somers, D.O.,Neu, M.,Stuckey, J.; THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000250; to be published,

Experimental method

X-RAY DIFFRACTION (1.652 Å)