4YAY

XFEL structure of human Angiotensin Receptor

4YAY の概要

• エントリーDOI: 10.2210/pdb4yay/pdb
• 分子名称: Soluble cytochrome b562,Type-1 angiotensin II receptor, 5,7-diethyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-3,4-dihydro-1,6-naphthyridin-2(1H)-one (2 entities in total)
• 機能のキーワード: xfel, serial femtosecond crystallography, human angiotensin receptor at1r, bril, g protein-coupled receptor, gpcr, gpcr network, lipidic cubic phase, lcp, membrane protein, structural genomics, zd7155, angiotensin receptor blocker, room temperature, psi-biology
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 47679.23

構造登録者

Zhang, H.,Unal, H.,Gati, C.,Han, G.W.,Zatsepin, N.A.,James, D.,Wang, D.,Nelson, G.,Weierstall, U.,Messerschmidt, M.,Williams, G.J.,Boutet, S.,Yefanov, O.M.,White, T.A.,Liu, W.,Ishchenko, A.,Tirupula, K.C.,Desnoyer, R.,Sawaya, M.C.,Xu, Q.,Coe, J.,Cornrad, C.E.,Fromme, P.,Stevens, R.C.,Katritch, V.,Karnik, S.S.,Cherezov, V.,GPCR Network (GPCR) (登録日: 2015-02-18, 公開日: 2015-04-22, 最終更新日: 2023-08-16)

• 主引用文献: Zhang, H.,Unal, H.,Gati, C.,Han, G.W.,Liu, W.,Zatsepin, N.A.,James, D.,Wang, D.,Nelson, G.,Weierstall, U.,Sawaya, M.R.,Xu, Q.,Messerschmidt, M.,Williams, G.J.,Boutet, S.,Yefanov, O.M.,White, T.A.,Wang, C.,Ishchenko, A.,Tirupula, K.C.,Desnoyer, R.,Coe, J.,Conrad, C.E.,Fromme, P.,Stevens, R.C.,Katritch, V.,Karnik, S.S.,Cherezov, V.; Structure of the Angiotensin receptor revealed by serial femtosecond crystallography.; Cell, 161:833-844, 2015; PubMed: 25913193; DOI: 10.1016/j.cell.2015.04.011

実験手法

X-RAY DIFFRACTION (2.9 Å)