4Y5Y
Diabody 330 complex with EpoR
Summary for 4Y5Y
Entry DOI | 10.2210/pdb4y5y/pdb |
Related | 4Y5V 4Y5X |
Descriptor | diabody 330 VH domain, diabody 330 VL domain, Erythropoietin receptor, ... (5 entities in total) |
Functional Keywords | diabody complex, receptor, protein binding-immune system complex, protein binding/immune system |
Biological source | Homo sapiens More |
Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform EPOR-S: Secreted : P19235 |
Total number of polymer chains | 6 |
Total formula weight | 102428.44 |
Authors | Moraga, I.,Guo, F.,Ozkan, E.,Jude, K.M.,Garcia, K.C. (deposition date: 2015-02-12, release date: 2015-03-18, Last modification date: 2023-09-27) |
Primary citation | Moraga, I.,Wernig, G.,Wilmes, S.,Gryshkova, V.,Richter, C.P.,Hong, W.J.,Sinha, R.,Guo, F.,Fabionar, H.,Wehrman, T.S.,Krutzik, P.,Demharter, S.,Plo, I.,Weissman, I.L.,Minary, P.,Majeti, R.,Constantinescu, S.N.,Piehler, J.,Garcia, K.C. Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands. Cell, 160:1196-1208, 2015 Cited by PubMed: 25728669DOI: 10.1016/j.cell.2015.02.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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