4Y0U
Crystal Structure of 6Alpha-Hydroxymethylpenicillanate Complexed with OXA-58, a Carbapenem hydrolyzing Class D betalactamase from Acinetobacter baumanii.
Summary for 4Y0U
Entry DOI | 10.2210/pdb4y0u/pdb |
Related | 4Y0O 4Y0T |
Descriptor | Beta-lactamase, 2-(1-CARBOXY-2-HYDROXY-ETHYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID (3 entities in total) |
Functional Keywords | acyl-enzyme complex, oxa-58, 6alpha-hydroxymethylpenicillanate, hydrolase |
Biological source | Acinetobacter baumannii |
Total number of polymer chains | 4 |
Total formula weight | 126989.97 |
Authors | Pratap, S.,Katiki, M.,Gill, P.,Golemi-Kotra, D.,Kumar, P. (deposition date: 2015-02-06, release date: 2016-01-13) |
Primary citation | Pratap, S.,Katiki, M.,Gill, P.,Kumar, P.,Golemi-Kotra, D. Active-Site Plasticity Is Essential to Carbapenem Hydrolysis by OXA-58 Class D beta-Lactamase of Acinetobacter baumannii. Antimicrob.Agents Chemother., 60:75-86, 2015 Cited by PubMed: 26459904DOI: 10.1128/AAC.01393-15 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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