4XYJ
Crystal structure of human phosphofructokinase-1 in complex with ATP and Mg, Northeast Structural Genomics Consortium Target HR9275
Summary for 4XYJ
Entry DOI | 10.2210/pdb4xyj/pdb |
Related | 4XYK |
Descriptor | ATP-dependent 6-phosphofructokinase, platelet type, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | transferase, structural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium, nesg |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 8 |
Total formula weight | 718837.36 |
Authors | Forouhar, F.,Webb, B.A.,Szu, F.-E.,Seetharaman, J.,Barber, D.L.,Tong, L.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2015-02-02, release date: 2015-05-20, Last modification date: 2023-09-27) |
Primary citation | Webb, B.A.,Forouhar, F.,Szu, F.E.,Seetharaman, J.,Tong, L.,Barber, D.L. Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature, 523:111-114, 2015 Cited by PubMed: 25985179DOI: 10.1038/nature14405 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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