4XYJ

Crystal structure of human phosphofructokinase-1 in complex with ATP and Mg, Northeast Structural Genomics Consortium Target HR9275

4XYJ の概要

• エントリーDOI: 10.2210/pdb4xyj/pdb
• 関連するPDBエントリー: 4XYK
• 分子名称: ATP-dependent 6-phosphofructokinase, platelet type, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: transferase, structural genomics, psi-biology, protein structure initiative, northeast structural genomics consortium, nesg
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 718837.36

構造登録者

Forouhar, F.,Webb, B.A.,Szu, F.-E.,Seetharaman, J.,Barber, D.L.,Tong, L.,Northeast Structural Genomics Consortium (NESG) (登録日: 2015-02-02, 公開日: 2015-05-20, 最終更新日: 2023-09-27)

• 主引用文献: Webb, B.A.,Forouhar, F.,Szu, F.E.,Seetharaman, J.,Tong, L.,Barber, D.L.; Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations.; Nature, 523:111-114, 2015; PubMed: 25985179; DOI: 10.1038/nature14405

実験手法

X-RAY DIFFRACTION (3.1 Å)