4XUJ
Nucleosome core particle containing adducts from treatment with a thiomorpholine-substituted [(eta-6-p-cymene)Ru(3-hydroxy-2-pyridone)Cl] compound
Summary for 4XUJ
Entry DOI | 10.2210/pdb4xuj/pdb |
Descriptor | Histone H3.2, Histone H4, Histone H2A, ... (10 entities in total) |
Functional Keywords | nucleosome, ruthenium agent, dna-bindig protein-dna complex, dna-binding protein-dna complex, dna-binding protein/dna |
Biological source | Xenopus laevis (African clawed frog) More |
Cellular location | Nucleus: P84233 P62799 Q6AZJ8 P02281 |
Total number of polymer chains | 10 |
Total formula weight | 199153.51 |
Authors | Adhireksan, Z.,Davey, C.A. (deposition date: 2015-01-26, release date: 2016-01-27, Last modification date: 2023-11-08) |
Primary citation | Hanif, M.,Meier, S.M.,Adhireksan, Z.,Henke, H.,Martic, S.,Labib, M.,Kandioller, W.,Jakupec, M.A.,Kraatz, H.B.,Davey, C.A.,Keppler, B.K.,Hartinger, C.G. Contrasting Cytotoxicity and Reactivity of RuII-Arene Complexes of Morpholine vs Thiomorpholine Substituted 3-Hydroxy-2-pyridone Ligands To Be Published, |
Experimental method | X-RAY DIFFRACTION (3.18 Å) |
Structure validation
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