4XNY
Crystal structure of broadly and potently neutralizing antibody VRC08C in complex with HIV-1 clade A strain Q842.d12 gp120
Summary for 4XNY
Entry DOI | 10.2210/pdb4xny/pdb |
Related | 3NGB 4XMP 4XNZ |
Descriptor | Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160, HEAVY CHAIN OF ANTIBODY VRC08C, LIGHT CHAIN OF ANTIBODY VRC08C, ... (5 entities in total) |
Functional Keywords | antibody, hiv-1, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 3 |
Total formula weight | 90325.04 |
Authors | Zhou, T.,Srivatsan, S.,Kwong, P.D. (deposition date: 2015-01-16, release date: 2015-04-29, Last modification date: 2023-09-27) |
Primary citation | Wu, X.,Zhang, Z.,Schramm, C.A.,Joyce, M.G.,Do Kwon, Y.,Zhou, T.,Sheng, Z.,Zhang, B.,O'Dell, S.,McKee, K.,Georgiev, I.S.,Chuang, G.Y.,Longo, N.S.,Lynch, R.M.,Saunders, K.O.,Soto, C.,Srivatsan, S.,Yang, Y.,Bailer, R.T.,Louder, M.K.,Mullikin, J.C.,Connors, M.,Kwong, P.D.,Mascola, J.R.,Shapiro, L. Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell, 161:470-485, 2015 Cited by PubMed: 25865483DOI: 10.1016/j.cell.2015.03.004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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