4XNY
Crystal structure of broadly and potently neutralizing antibody VRC08C in complex with HIV-1 clade A strain Q842.d12 gp120
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | G | Envelope glycoprotein gp160,Envelope glycoprotein gp160,Envelope glycoprotein gp160 | polymer | 354 | 39667.8 | 1 | UniProt (Q8JDI3) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
2 | H | HEAVY CHAIN OF ANTIBODY VRC08C | polymer | 235 | 25296.4 | 1 | Pfam (PF07654) UniProt (by SIFTS) (P01857) In PDB | Homo sapiens (Human) | |
3 | L | LIGHT CHAIN OF ANTIBODY VRC08C | polymer | 211 | 22927.5 | 1 | Pfam (PF07654) UniProt (by SIFTS) (P01834) In PDB | Homo sapiens (Human) | |
4 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 11 | Chemie (NAG) | |||
5 | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
G: 44 - 123 (UniProt: Q8JDI3)
G: 199 - 317 (UniProt: Q8JDI3)
G: 324 - 492 (UniProt: Q8JDI3)
G: 199 - 317 (UniProt: Q8JDI3)
PDB | External Database | Details |
---|---|---|
Gly 124 | - | linker |
Gly 198 | - | linker |
PDB | External Database | Details |
---|---|---|
Gly 318 | - | linker |
Gly 319 | - | linker |
Ser 320 | - | linker |
Gly 321 | - | linker |
Ser 322 | - | linker |
Gly 323 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 87891.8 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 2433.3 | |
All* | Total formula weight | 90325.0 |