4XF7
myo-inositol 3-kinase bound with its substrates (AMPPCP and myo-inositol)
Summary for 4XF7
| Entry DOI | 10.2210/pdb4xf7/pdb |
| Related | 4XF7 |
| Descriptor | Carbohydrate/pyrimidine kinase, PfkB family, 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (6 entities in total) |
| Functional Keywords | ribokinase, substrate complex, transferase |
| Biological source | Thermococcus kodakaraensis KOD1 |
| Total number of polymer chains | 2 |
| Total formula weight | 64894.81 |
| Authors | Nagata, R.,Fujihashi, M.,Miki, K. (deposition date: 2014-12-26, release date: 2015-06-03, Last modification date: 2023-11-08) |
| Primary citation | Nagata, R.,Fujihashi, M.,Sato, T.,Atomi, H.,Miki, K. Crystal Structure and Product Analysis of an Archaeal myo-Inositol Kinase Reveal Substrate Recognition Mode and 3-OH Phosphorylation Biochemistry, 54:3494-3503, 2015 Cited by PubMed: 25972008DOI: 10.1021/acs.biochem.5b00296 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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