4XDW
Crystal Structure of the L74F/M78V/I80V/L114F mutant of LEH
Summary for 4XDW
Entry DOI | 10.2210/pdb4xdw/pdb |
Related | 4xbt 4xbx 4xby 4xdv |
Descriptor | Limonene-1,2-epoxide hydrolase (2 entities in total) |
Functional Keywords | epoxide hydrolase, hydrolase |
Biological source | Rhodococcus erythropolis |
Total number of polymer chains | 8 |
Total formula weight | 138955.05 |
Authors | Kong, X.D.,Sun, Z.,Lonsdale, R.,Xu, J.H.,Reetz, M.T.,Zhou, J. (deposition date: 2014-12-20, release date: 2015-07-15, Last modification date: 2023-11-08) |
Primary citation | Sun, Z.,Lonsdale, R.,Kong, X.D.,Xu, J.H.,Zhou, J.,Reetz, M.T. Reshaping an Enzyme Binding Pocket for Enhanced and Inverted Stereoselectivity: Use of Smallest Amino Acid Alphabets in Directed Evolution Angew.Chem.Int.Ed.Engl., 54:12410-12415, 2015 Cited by PubMed: 25891639DOI: 10.1002/anie.201501809 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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