4XDW
Crystal Structure of the L74F/M78V/I80V/L114F mutant of LEH
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0018744 | molecular_function | limonene-1,2-epoxide hydrolase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0018744 | molecular_function | limonene-1,2-epoxide hydrolase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0018744 | molecular_function | limonene-1,2-epoxide hydrolase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0018744 | molecular_function | limonene-1,2-epoxide hydrolase activity |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0018744 | molecular_function | limonene-1,2-epoxide hydrolase activity |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0018744 | molecular_function | limonene-1,2-epoxide hydrolase activity |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0018744 | molecular_function | limonene-1,2-epoxide hydrolase activity |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0018744 | molecular_function | limonene-1,2-epoxide hydrolase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | ACT_SITE: Proton donor => ECO:0000305 |
| Chain | Residue | Details |
| A | ASP101 | |
| E | ASP101 | |
| G | ASP101 | |
| B | ASP101 | |
| F | ASP101 | |
| H | ASP101 | |
| C | ASP101 | |
| D | ASP101 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305 |
| Chain | Residue | Details |
| A | ASP132 | |
| E | ASP132 | |
| G | ASP132 | |
| B | ASP132 | |
| F | ASP132 | |
| H | ASP132 | |
| C | ASP132 | |
| D | ASP132 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 644 |
| Chain | Residue | Details |
| A | TYR53 | electrostatic stabiliser |
| A | ASN55 | electrostatic stabiliser |
| A | ARG99 | electrostatic stabiliser, proton acceptor, proton donor, proton relay |
| A | ASP101 | proton acceptor, proton donor |
| A | ASP132 | activator, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 644 |
| Chain | Residue | Details |
| E | TYR53 | electrostatic stabiliser |
| E | ASN55 | electrostatic stabiliser |
| E | ARG99 | electrostatic stabiliser, proton acceptor, proton donor, proton relay |
| E | ASP101 | proton acceptor, proton donor |
| E | ASP132 | activator, proton acceptor, proton donor |
| site_id | MCSA3 |
| Number of Residues | 5 |
| Details | M-CSA 644 |
| Chain | Residue | Details |
| G | TYR53 | electrostatic stabiliser |
| G | ASN55 | electrostatic stabiliser |
| G | ARG99 | electrostatic stabiliser, proton acceptor, proton donor, proton relay |
| G | ASP101 | proton acceptor, proton donor |
| G | ASP132 | activator, proton acceptor, proton donor |
| site_id | MCSA4 |
| Number of Residues | 5 |
| Details | M-CSA 644 |
| Chain | Residue | Details |
| B | TYR53 | electrostatic stabiliser |
| B | ASN55 | electrostatic stabiliser |
| B | ARG99 | electrostatic stabiliser, proton acceptor, proton donor, proton relay |
| B | ASP101 | proton acceptor, proton donor |
| B | ASP132 | activator, proton acceptor, proton donor |
| site_id | MCSA5 |
| Number of Residues | 5 |
| Details | M-CSA 644 |
| Chain | Residue | Details |
| F | TYR53 | electrostatic stabiliser |
| F | ASN55 | electrostatic stabiliser |
| F | ARG99 | electrostatic stabiliser, proton acceptor, proton donor, proton relay |
| F | ASP101 | proton acceptor, proton donor |
| F | ASP132 | activator, proton acceptor, proton donor |
| site_id | MCSA6 |
| Number of Residues | 5 |
| Details | M-CSA 644 |
| Chain | Residue | Details |
| H | TYR53 | electrostatic stabiliser |
| H | ASN55 | electrostatic stabiliser |
| H | ARG99 | electrostatic stabiliser, proton acceptor, proton donor, proton relay |
| H | ASP101 | proton acceptor, proton donor |
| H | ASP132 | activator, proton acceptor, proton donor |
| site_id | MCSA7 |
| Number of Residues | 5 |
| Details | M-CSA 644 |
| Chain | Residue | Details |
| C | TYR53 | electrostatic stabiliser |
| C | ASN55 | electrostatic stabiliser |
| C | ARG99 | electrostatic stabiliser, proton acceptor, proton donor, proton relay |
| C | ASP101 | proton acceptor, proton donor |
| C | ASP132 | activator, proton acceptor, proton donor |
| site_id | MCSA8 |
| Number of Residues | 5 |
| Details | M-CSA 644 |
| Chain | Residue | Details |
| D | TYR53 | electrostatic stabiliser |
| D | ASN55 | electrostatic stabiliser |
| D | ARG99 | electrostatic stabiliser, proton acceptor, proton donor, proton relay |
| D | ASP101 | proton acceptor, proton donor |
| D | ASP132 | activator, proton acceptor, proton donor |
