4XDO
Crystal structure of human KDM4C catalytic domain with OGA
Summary for 4XDO
Entry DOI | 10.2210/pdb4xdo/pdb |
Related | 2xml 4XDP |
Descriptor | Lysine-specific demethylase 4C, ZINC ION, FE (III) ION, ... (8 entities in total) |
Functional Keywords | lysine-specific demethylase 4c, oxidoreductase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : Q9H3R0 |
Total number of polymer chains | 2 |
Total formula weight | 79905.39 |
Authors | Swinger, K.K.,Boriack-Sjodin, P.A. (deposition date: 2014-12-19, release date: 2015-03-25, Last modification date: 2024-02-28) |
Primary citation | Wigle, T.J.,Swinger, K.K.,Campbell, J.E.,Scholle, M.D.,Sherrill, J.,Admirand, E.A.,Boriack-Sjodin, P.A.,Kuntz, K.W.,Chesworth, R.,Moyer, M.P.,Scott, M.P.,Copeland, R.A. A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening. J Biomol Screen, 20:810-820, 2015 Cited by PubMed: 25755264DOI: 10.1177/1087057115575689 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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