4X6Z
Yeast 20S proteasome in complex with PR-VI modulator
Summary for 4X6Z
Entry DOI | 10.2210/pdb4x6z/pdb |
Descriptor | Proteasome subunit beta type-6, Proteasome subunit beta type-1, Proteasome subunit beta type-2, ... (19 entities in total) |
Functional Keywords | 20s proteasome, low-molecular mass activators, allosteric regulation, hydrolase |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Cellular location | Cytoplasm: P23724 P38624 P25043 P25451 P22141 P30656 P30657 P21243 P23639 P23638 P40303 P32379 P40302 P21242 |
Total number of polymer chains | 30 |
Total formula weight | 776078.35 |
Authors | Rostankowski, R.,Witkowska, J.,Borek, D.,Otwinowski, Z.,Jankowska, E. (deposition date: 2014-12-09, release date: 2015-12-23, Last modification date: 2024-01-10) |
Primary citation | Witkowska, J.,Rostankowski, R.,Dubin, G.,Grudnik, P.,Golik, P.,Gaczynska, M.,Osmulski, P.,Borek, D.,Otwinowski, Z.,Jankowska, E. Crystal structures revealed the common place of binding of low-molecular mass activators with the 20S proteasome To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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