4X67

Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions.

Summary for 4X67

• Entry DOI: 10.2210/pdb4x67/pdb
• Related: 4X6A
• Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerases I, II, and III subunit RPABC4, RNA_9 mer, ... (13 entities in total)
• Functional Keywords: pol ii elongation complex oxidative cyclopurine dna lesions, transcription-dna complex, transcription/dna
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 12
• Total formula weight: 481979.81

Authors

Wang, L.,Chong, J.,Wang, D. (deposition date: 2014-12-07, release date: 2015-02-04, Last modification date: 2019-12-25)

• Primary citation: Walmacq, C.,Wang, L.,Chong, J.,Scibelli, K.,Lubkowska, L.,Gnatt, A.,Brooks, P.J.,Wang, D.,Kashlev, M.; Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.; Proc.Natl.Acad.Sci.USA, 112:E410-E419, 2015; PubMed: 25605892; DOI: 10.1073/pnas.1415186112

Experimental method

X-RAY DIFFRACTION (4.1 Å)