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4X5V

Crystal structure of the post-catalytic nick complex of DNA polymerase lambda with a templating A and incorporated 8-oxo-dGMP

Summary for 4X5V
Entry DOI10.2210/pdb4x5v/pdb
DescriptorDNA polymerase lambda, DNA (5'-D(P*GP*CP*CP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*AP*CP*(8OG))-3'), ... (8 entities in total)
Functional Keywordsdna polymerase lambda, protein-dna complex, helix-hairpin-helix, transferase-dna complex, transferase/dna
Biological sourceHomo sapiens (Human)
More
Cellular locationNucleus: Q9UGP5
Total number of polymer chains4
Total formula weight43392.46
Authors
Burak, M.J.,Guja, K.E.,Garcia-Diaz, M. (deposition date: 2014-12-05, release date: 2015-10-28, Last modification date: 2024-02-28)
Primary citationBurak, M.J.,Guja, K.E.,Garcia-Diaz, M.
Nucleotide binding interactions modulate dNTP selectivity and facilitate 8-oxo-dGTP incorporation by DNA polymerase lambda.
Nucleic Acids Res., 43:8089-8099, 2015
Cited by
PubMed: 26220180
DOI: 10.1093/nar/gkv760
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.15 Å)
Structure validation

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