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4X5V

Crystal structure of the post-catalytic nick complex of DNA polymerase lambda with a templating A and incorporated 8-oxo-dGMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase lambdapolymer32536448.61UniProt (Q9UGP5)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)Pol Lambda,DNA polymerase beta-2,Pol beta2,DNA polymerase kappa
2B
(D)
DNA (5'-D(P*GP*CP*CP*G)-3')polymer41191.81synthetic construct
3C
(P)
DNA (5'-D(*CP*AP*GP*TP*AP*CP*(8OG))-3')polymer72138.41synthetic construct
4D
(T)
DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3')polymer113374.21synthetic construct
5E
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
6F
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
7G
(A)
CITRIC ACIDnon-polymer192.11Chemie (CIT)
8H, I, J, K
(A, D, P, T)
waterwater18.0180Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight43153.0
Non-Polymers*Number of molecules3
Total formula weight239.4
All*Total formula weight43392.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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