4X3E
Crystal structure of EED in complex with a trimethylated Jarid2 peptide
Summary for 4X3E
Entry DOI | 10.2210/pdb4x3e/pdb |
Descriptor | Polycomb protein EED, ALA-GLN-ARG-M3L-PHE-ALA-GLN-SER (3 entities in total) |
Functional Keywords | gene regulation, histone binding, wd40, transcription |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: O75530 |
Total number of polymer chains | 2 |
Total formula weight | 43983.06 |
Authors | Justin, N.,Gamblin, S.J.,Margueron, R. (deposition date: 2014-11-28, release date: 2015-01-21, Last modification date: 2024-01-10) |
Primary citation | Sanulli, S.,Justin, N.,Teissandier, A.,Ancelin, K.,Portoso, M.,Caron, M.,Michaud, A.,Lombard, B.,da Rocha, S.T.,Offer, J.,Loew, D.,Servant, N.,Wassef, M.,Burlina, F.,Gamblin, S.J.,Heard, E.,Margueron, R. Jarid2 Methylation via the PRC2 Complex Regulates H3K27me3 Deposition during Cell Differentiation. Mol.Cell, 57:769-783, 2015 Cited by PubMed: 25620564DOI: 10.1016/j.molcel.2014.12.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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