4WZC

Understanding Extradiol Dioxygenase Mechanism in NAD+ Biosynthesis by Viewing Catalytic Intermediates - 2,3-cis-4,5-trans ACMS bound to I142A mutant HAO

Summary for 4WZC

• Entry DOI: 10.2210/pdb4wzc/pdb
• Related: 4R52
• Descriptor: 3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION, (2E)-2-amino-3-[(1E)-3-oxoprop-1-en-1-yl]but-2-enedioic acid, ... (4 entities in total)
• Functional Keywords: bi-cupin iron-binding, dioxygenase, oxidoreductase
• Biological source: Ralstonia metallidurans
• Total number of polymer chains: 1
• Total formula weight: 20725.82

Authors

Liu, F.,Liu, A. (deposition date: 2014-11-19, release date: 2016-02-10, Last modification date: 2023-09-27)

• Primary citation: Liu, F.,Liu, A.; Probing Extradiol Dioxygenase Mechanism in NAD+ Biosynthesis by Viewing Reaction Cycle Intermediates; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.842 Å)