4WZC
Understanding Extradiol Dioxygenase Mechanism in NAD+ Biosynthesis by Viewing Catalytic Intermediates - 2,3-cis-4,5-trans ACMS bound to I142A mutant HAO
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 3-hydroxyanthranilate 3,4-dioxygenase | polymer | 177 | 20429.0 | 1 | UniProt (Q1LCS4) Pfam (PF06052) In PDB | Ralstonia metallidurans | 3-hydroxyanthranilate oxygenase,3-HAO,3-hydroxyanthranilic acid dioxygenase,HAD |
2 | A | FE (II) ION | non-polymer | 55.8 | 2 | Chemie (FE2) | |||
3 | A | (2E)-2-amino-3-[(1E)-3-oxoprop-1-en-1-yl]but-2-enedioic acid | non-polymer | 185.1 | 1 | Chemie (1UC) | |||
4 | water | water | 18.0 | 98 | Chemie (HOH) |
Sequence modifications
A: 1 - 174 (UniProt: Q1LCS4)
PDB | External Database | Details |
---|---|---|
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Ala 142 | Ile 142 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 20429.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 296.8 | |
All* | Total formula weight | 20725.8 |