4WYZ

The crystal structure of the A109G mutant of RNase A in complex with 3'UMP

Summary for 4WYZ

• Entry DOI: 10.2210/pdb4wyz/pdb
• Related: 4WYN 4WYP
• Descriptor: Ribonuclease pancreatic, 3'-URIDINEMONOPHOSPHATE (3 entities in total)
• Functional Keywords: conformational dynamics, hydrolase
• Biological source: Bos taurus (Bovine)
• Total number of polymer chains: 2
• Total formula weight: 28299.35

Authors

French, R.L.,Gagne, D.,Doucet, N.,Simonovic, M. (deposition date: 2014-11-18, release date: 2015-11-18, Last modification date: 2019-12-25)

• Primary citation: Gagne, D.,French, R.L.,Narayanan, C.,Simonovic, M.,Agarwal, P.K.,Doucet, N.; Perturbation of the Conformational Dynamics of an Active-Site Loop Alters Enzyme Activity.; Structure, 23:2256-2266, 2015; PubMed: 26655472; DOI: 10.1016/j.str.2015.10.011

Experimental method

X-RAY DIFFRACTION (1.449 Å)