4WUR
The crystal structure of the MERS-CoV papain-like protease (C111S) with human ubiquitin
4WUR の概要
エントリーDOI | 10.2210/pdb4wur/pdb |
関連するPDBエントリー | 4P16 |
分子名称 | Papain-like protease, Polyubiquitin-B, ISOPROPYL ALCOHOL, ... (4 entities in total) |
機能のキーワード | mers-cov, papain-like protease, ubiquitin, complex, hydrolase |
由来する生物種 | Human coronavirus EMC (HCoV-EMC) 詳細 |
細胞内の位置 | Papain-like proteinase: Host membrane; Multi-pass membrane protein. Non-structural protein 4: Host membrane; Multi-pass membrane protein. Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region . Helicase: Host endoplasmic reticulum-Golgi intermediate compartment . Uridylate-specific endoribonuclease: Host cytoplasm, host perinuclear region : K9N7C7 Ubiquitin: Cytoplasm : P0CG47 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 44917.97 |
構造登録者 | |
主引用文献 | Lei, J.,Hilgenfeld, R. Structural and mutational analysis of the interaction between the Middle-East respiratory syndrome coronavirus (MERS-CoV) papain-like protease and human ubiquitin. Virol Sin, 31:288-299, 2016 Cited by PubMed: 27245450DOI: 10.1007/s12250-016-3742-4 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3.16 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード