4WTV

Crystal structure of the phosphatidylinositol 4-kinase IIbeta

4WTV の概要

• エントリーDOI: 10.2210/pdb4wtv/pdb
• 分子名称: Phosphatidylinositol 4-kinase type 2-beta,Endolysin,Phosphatidylinositol 4-kinase type 2-beta, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
• 機能のキーワード: lipid kinase, phosphatidyl inositol, transferase, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm: Q8TCG2
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 119750.16

構造登録者

Klima, M.,Baumlova, A.,Chalupska, D.,Boura, E. (登録日: 2014-10-30, 公開日: 2015-07-15, 最終更新日: 2024-01-10)

• 主引用文献: Klima, M.,Baumlova, A.,Chalupska, D.,Hrebabecky, H.,Dejmek, M.,Nencka, R.,Boura, E.; The high-resolution crystal structure of phosphatidylinositol 4-kinase II beta and the crystal structure of phosphatidylinositol 4-kinase II alpha containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design.; Acta Crystallogr.,Sect.D, 71:1555-1563, 2015; PubMed: 26143926; DOI: 10.1107/S1399004715009505

実験手法

X-RAY DIFFRACTION (1.9 Å)