4WSN

Crystal structure of the COP9 signalosome, a P1 crystal form

This is a non-PDB format compatible entry.

Summary for 4WSN

• Entry DOI: 10.2210/pdb4wsn/pdb
• Related: 4d10 4d18
• Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... (9 entities in total)
• Functional Keywords: signaling protein, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 48
• Total formula weight: 1935485.77

Authors

Bunker, R.D.,Lingaraju, G.M.,Thoma, N.H. (deposition date: 2014-10-28, release date: 2015-12-23, Last modification date: 2024-01-10)

• Primary citation: Cavadini, S.,Fischer, E.S.,Bunker, R.D.,Potenza, A.,Lingaraju, G.M.,Goldie, K.N.,Mohamed, W.I.,Faty, M.,Petzold, G.,Beckwith, R.E.,Tichkule, R.B.,Hassiepen, U.,Abdulrahman, W.,Pantelic, R.S.,Matsumoto, S.,Sugasawa, K.,Stahlberg, H.,Thoma, N.H.; Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome.; Nature, 531:598-603, 2016; PubMed: 27029275; DOI: 10.1038/nature17416

Experimental method

X-RAY DIFFRACTION (5.5 Å)