4WQO
Structure of VHL-EloB-EloC-Cul2
Summary for 4WQO
Entry DOI | 10.2210/pdb4wqo/pdb |
Descriptor | Von Hippel-Lindau disease tumor suppressor, Transcription elongation factor B polypeptide 2, Transcription elongation factor B polypeptide 1, ... (4 entities in total) |
Functional Keywords | e3 ligase complex, transcription |
Biological source | Homo sapiens (Human) More |
Cellular location | Isoform 1: Cytoplasm. Isoform 3: Cytoplasm: P40337 Nucleus : Q15370 Q15369 |
Total number of polymer chains | 4 |
Total formula weight | 72474.79 |
Authors | Nguyen, H.C.,Xiong, Y. (deposition date: 2014-10-22, release date: 2015-03-04, Last modification date: 2023-09-27) |
Primary citation | Nguyen, H.C.,Yang, H.,Fribourgh, J.L.,Wolfe, L.S.,Xiong, Y. Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex. Structure, 23:441-449, 2015 Cited by PubMed: 25661653DOI: 10.1016/j.str.2014.12.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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