4WPG

Group A Streptococcus GacA is an essential dTDP-4-dehydrorhamnose reductase (RmlD)

Summary for 4WPG

• Entry DOI: 10.2210/pdb4wpg/pdb
• Descriptor: dTDP-4-dehydrorhamnose reductase, (4S)-2-METHYL-2,4-PENTANEDIOL, (4R)-2-METHYLPENTANE-2,4-DIOL, ... (5 entities in total)
• Functional Keywords: rmld, dtdp-4-dehydrorhamnose reductase, oxidoreductase
• Biological source: Streptococcus pyogenes
• Total number of polymer chains: 1
• Total formula weight: 32866.85

Authors

van der Beek, S.L.,Le Breton, Y.,Ferenbach, A.T.,van Aalten, D.M.F.,Navratilova, I.,McIver, K.,van Sorge, N.M.,Dorfmueller, H.C. (deposition date: 2014-10-18, release date: 2015-09-09, Last modification date: 2024-05-08)

• Primary citation: van der Beek, S.L.,Le Breton, Y.,Ferenbach, A.T.,Chapman, R.N.,van Aalten, D.M.,Navratilova, I.,Boons, G.J.,McIver, K.S.,van Sorge, N.M.,Dorfmueller, H.C.; GacA is essential for Group A Streptococcus and defines a new class of monomeric dTDP-4-dehydrorhamnose reductases (RmlD).; Mol.Microbiol., 98:946-962, 2015; PubMed: 26278404; DOI: 10.1111/mmi.13169

Experimental method

X-RAY DIFFRACTION (1.1 Å)