4WPG
Group A Streptococcus GacA is an essential dTDP-4-dehydrorhamnose reductase (RmlD)
Summary for 4WPG
Entry DOI | 10.2210/pdb4wpg/pdb |
Descriptor | dTDP-4-dehydrorhamnose reductase, (4S)-2-METHYL-2,4-PENTANEDIOL, (4R)-2-METHYLPENTANE-2,4-DIOL, ... (5 entities in total) |
Functional Keywords | rmld, dtdp-4-dehydrorhamnose reductase, oxidoreductase |
Biological source | Streptococcus pyogenes |
Total number of polymer chains | 1 |
Total formula weight | 32866.85 |
Authors | van der Beek, S.L.,Le Breton, Y.,Ferenbach, A.T.,van Aalten, D.M.F.,Navratilova, I.,McIver, K.,van Sorge, N.M.,Dorfmueller, H.C. (deposition date: 2014-10-18, release date: 2015-09-09, Last modification date: 2024-05-08) |
Primary citation | van der Beek, S.L.,Le Breton, Y.,Ferenbach, A.T.,Chapman, R.N.,van Aalten, D.M.,Navratilova, I.,Boons, G.J.,McIver, K.S.,van Sorge, N.M.,Dorfmueller, H.C. GacA is essential for Group A Streptococcus and defines a new class of monomeric dTDP-4-dehydrorhamnose reductases (RmlD). Mol.Microbiol., 98:946-962, 2015 Cited by PubMed: 26278404DOI: 10.1111/mmi.13169 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
Download full validation report