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4WPG

Group A Streptococcus GacA is an essential dTDP-4-dehydrorhamnose reductase (RmlD)

Functional Information from GO Data
ChainGOidnamespacecontents
A0005829cellular_componentcytosol
A0006556biological_processS-adenosylmethionine biosynthetic process
A0008831molecular_functiondTDP-4-dehydrorhamnose reductase activity
A0016491molecular_functionoxidoreductase activity
A0019305biological_processdTDP-rhamnose biosynthetic process
A0045226biological_processextracellular polysaccharide biosynthetic process
A0048269cellular_componentmethionine adenosyltransferase complex
A0048270molecular_functionmethionine adenosyltransferase regulator activity
Functional Information from PDB Data
site_idAC1
Number of Residues8
Detailsbinding site for residue MPD A 301
ChainResidue
AGLU0
ALEU19
AARG22
ATYR55
AARG174
ACYS196
ATHR199
AGLU200

site_idAC2
Number of Residues7
Detailsbinding site for residue MRD A 302
ChainResidue
ATHR52
ATHR95
ATHR199
AHOH432
AHOH507
AHOH571
AGLU0

site_idAC3
Number of Residues3
Detailsbinding site for residue PO4 A 303
ChainResidue
ATRP220
AHOH527
AHOH834

221051

PDB entries from 2024-06-12

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