4WL8

Crystal Structure of Mtb PEPCK in complex with non-hydrolyzable analog of GTP

Summary for 4WL8

• Entry DOI: 10.2210/pdb4wl8/pdb
• Related: 4WIE 4WIU
• Descriptor: Phosphoenolpyruvate carboxykinase [GTP], PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, GLYCEROL, ... (5 entities in total)
• Functional Keywords: gtp-dependent pepck, p-loop, r-loop, omega-loop, rate-limiting gluconeogenic enzyme, kinase, phosphoryl transfer, metal binding, lyase, transferase
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cytoplasm : A5TYT6
• Total number of polymer chains: 1
• Total formula weight: 69715.96

Authors

Kim, H.L.,Sacchettini, J.C. (deposition date: 2014-10-06, release date: 2015-10-21, Last modification date: 2023-09-27)

• Primary citation: Kim, H.L.; Crystal Structure of Mtb PEPCK in complex with non-hydrolyzable analog of GTP; to be published,

Experimental method

X-RAY DIFFRACTION (1.61 Å)