4WL8

Crystal Structure of Mtb PEPCK in complex with non-hydrolyzable analog of GTP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Phosphoenolpyruvate carboxykinase [GTP]	polymer	622	69046.7	1	UniProt (A5TYT6) Pfam (PF17297) Pfam (PF00821) In PDB	Mycobacterium tuberculosis	PEPCK
2	A	PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER	non-polymer		522.2	1	Chemie (GNP)
3	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	A	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
5		water	water		18.0	804	Chemie (HOH)

Sequence modifications

A: 1 - 606 (UniProt: A5TYT6)

PDB	External Database	Details
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Ala -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	69046.7
Non-Polymers*	Number of molecules	3
	Total formula weight	669.2
All*	Total formula weight	69716.0

*Water molecules are not included.