4WKG

The crystal structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic coop-erativity

4WKG の概要

• エントリーDOI: 10.2210/pdb4wkg/pdb
• 分子名称: Bifunctional polymyxin resistance protein ArnA, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: arna, multi-drug resistance, mdr, polymyxin, dehydrogenase, transformylase, cooperativity, allosteric regulation, transferase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 446741.23

構造登録者

Grimm, C. (登録日: 2014-10-02, 公開日: 2014-12-17, 最終更新日: 2024-01-10)

• 主引用文献: Fischer, U.,Hertlein, S.,Grimm, C.; The structure of apo ArnA features an unexpected central binding pocket and provides an explanation for enzymatic cooperativity.; Acta Crystallogr.,Sect.D, 71:687-696, 2015; PubMed: 25760615; DOI: 10.1107/S1399004714026686

実験手法

X-RAY DIFFRACTION (2.7 Å)